Immanuel F. Luescher
Ludwig Cancer Research(CH)
Publications by Year
Research Areas
Immunotherapy and Immune Responses, CAR-T cell therapy research, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Cancer Immunotherapy and Biomarkers
Most-Cited Works
- → Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients(2010)1,276 cited
- → A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.(1992)694 cited
- → CD8+ T Cells Specific for Tumor Antigens Can Be Rendered Dysfunctional by the Tumor Microenvironment through Upregulation of the Inhibitory Receptors BTLA and PD-1(2011)364 cited
- → Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex(2001)322 cited
- → T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion(2013)275 cited
- → Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3(2006)258 cited