Diane R. Sawicki

Publications by Year

Research Areas

Protein Tyrosine Phosphatases, Aldose Reductase and Taurine, Carbohydrate Chemistry and Synthesis, Bioactive Compounds and Antitumor Agents, Protein Kinase Regulation and GTPase Signaling

Most-Cited Works

• → Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications(2005)224 cited
• → Novel Benzofuran and Benzothiophene Biphenyls as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties(2000)210 cited
• → PTP1B Inhibition and Antihyperglycemic Activity in the ob/ob Mouse Model of Novel 11-Arylbenzo[b]naphtho[2,3-d]furans and 11-Arylbenzo[b]naphtho[2,3-d]thiophenes(1999)126 cited
• → New Azolidinediones as Inhibitors of Protein Tyrosine Phosphatase 1B with Antihyperglycemic Properties(2000)102 cited
• → Structural abnormalities do not explain the early functional abnormalities in the peripheral nerves of the streptozotocin diabetic rat(1999)48 cited
• → Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications(2004)48 cited
• → Polyol pathway activity in nervous tissues of diabetic and galactose-fed rats: Effect of dietary galactose withdrawal or tolrestat intervention therapy(1991)32 cited
• → Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74(2005)27 cited
• → Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications(2009)26 cited
• → Adenosine Triphosphatase Activity in Sciatic Nerve Tissue of Streptozocin-Induced Diabetic Rats with and without High Dietary Sucrose: Effect of Aldose Reductase Inhibitors(1991)19 cited