Spencer A. Freeman
University of Toronto(CA)SickKids Foundation(CA)
Publications by Year
Research Areas
Erythrocyte Function and Pathophysiology, Cell Adhesion Molecules Research, Cellular transport and secretion, Phagocytosis and Immune Regulation, PI3K/AKT/mTOR signaling in cancer
Most-Cited Works
- → Phagocytosis: receptors, signal integration, and the cytoskeleton(2014)535 cited
- → VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis(2017)271 cited
- → The cytoskeleton in phagocytosis and macropinocytosis(2021)243 cited
- → Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement(2018)239 cited
- → Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis(2023)218 cited
- → Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation(2005)209 cited
- → Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins(2015)209 cited
- → Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis(2016)200 cited
- → ( R )-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells(2014)187 cited
- → Control of the Hippo Pathway by Set7-Dependent Methylation of Yap(2013)160 cited