Jianshe Kong
WuXi AppTec (China)(CN)
Publications by Year
Research Areas
Fluorine in Organic Chemistry, Hepatitis C virus research, HIV/AIDS drug development and treatment, Asymmetric Hydrogenation and Catalysis, Chemical Synthesis and Reactions
Most-Cited Works
- → Discovery of (1 R ,5 S )- N -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( S )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( S )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection(2006)278 cited
- → Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor(2010)97 cited
- → Discovery of a vorapaxar analog with increased aqueous solubility(2010)21 cited
- → A Facile and Efficient Synthesis of 3,3-Dimethyl Isopropylidene Proline From (+)-3-Carene(2010)20 cited
- → A Unique Synthesis of 5,8-Difluoro-2H-chromene Using Silicone Oil as a Solvent(2015)7 cited
- → Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRASG12C Inhibitor ARS-2102(2022)4 cited
- → Regioselective Functionalization of 4-Methyl-1H-indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1H-indole(2017)2 cited
- → Syntheses of Potential Degradation Products of Phenylephrine in OTC Products(2008)1 cited
- → Preparation of Ethyl 1‐Benzyl‐4‐Fluoropiperidine‐4‐Carboxylate(2010)
- → Synthesis of Unnatural Amino Acids via Reductive C-C Bond Forming Hydrogenation(2005)