Jairam Palamanda
SK Life Science (United States)(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Computational Drug Discovery Methods, Statistical Methods in Clinical Trials, Antioxidant Activity and Oxidative Stress
Most-Cited Works
- → Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity(2008)267 cited
- → Involvement of vitamin E and protein thiols in the inhibition of microsomal lipid peroxidation by glutathione(1993)95 cited
- → Inhibition of protein carbonyl formation and lipid peroxidation by glutathione in rat liver microsomes(1992)74 cited
- → Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans(2015)59 cited
- → In Vitro Assessment of Drug-Drug Interaction Potential of Boceprevir Associated with Drug Metabolizing Enzymes and Transporters(2013)57 cited
- → Enzyme kinetic properties of human recombinant arylamine n-acetyltransferase 2 allotypic variants expressed in Escherichia coli(1995)55 cited
- → Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control(2017)46 cited
- → Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective(2016)45 cited
- Inhibition of CYP3A4 in a rapid microtiter plate assay using recombinant enzyme and in human liver microsomes using conventional substrates.(2001)
- → Metabolism-Based Identification of a Potent Thrombin Receptor Antagonist(2006)39 cited