Bonnie J Sperfslage
Kansas State University(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Bioactive Compounds and Antitumor Agents, Synthesis and Biological Evaluation, DNA Repair Mechanisms, Synthesis of Organic Compounds
Most-Cited Works
- → Syntheses and Bioactivities of Substituted 9,10-Dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetrones. Unusual Reactivities with Amines(2002)48 cited
- → Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling(2003)31 cited
- → A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines(2001)16 cited
- → Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro(2001)15 cited
- → Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro(2002)14 cited
- → Synthetic 1,4-anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines(2001)9 cited
- → Preparation and Cytotoxic Activity of Some New Rhodomycin Derivatives Bearing Modifications in the Sugar Moiety.(2002)8 cited
- Antileukemic activity of synthetic daunomycinone derivatives bearing modifications in the glycosidic moiety.(2002)
- → CCDC 175022: Experimental Crystal Structure Determination(2002)
- → ChemInform Abstract: Preparation and Cytotoxic Activity of Some New Rhodomycin Derivatives Bearing Modifications in the Sugar Moiety.(2002)