Gabriele Picco
Wellcome Sanger Institute(GB)Open Targets(GB)
Publications by Year
Research Areas
CRISPR and Genetic Engineering, DNA Repair Mechanisms, Genetic factors in colorectal cancer, Digestive system and related health, Pharmacogenetics and Drug Metabolism
Most-Cited Works
- → Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens(2019)1,391 cited
- → The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets(2015)305 cited
- → Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening(2019)131 cited
- → Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy(2021)112 cited
- → Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens(2020)110 cited
- → Minimal genome-wide human CRISPR-Cas9 library(2021)90 cited
- → Base editing screens map mutations affecting interferon-γ signaling in cancer(2023)84 cited
- → MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes(2015)75 cited
- → Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer(2019)75 cited
- → The RNA-binding protein ESRP1 promotes human colorectal cancer progression(2016)65 cited