Thomas J. Cradick
Atara Biotherapeutics (United States)(US)
Publications by Year
Research Areas
CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, RNA Interference and Gene Delivery, RNA and protein synthesis mechanisms, HIV Research and Treatment
Most-Cited Works
- → DNA targeting specificity of RNA-guided Cas9 nucleases(2013)4,831 cited
- → CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences(2014)641 cited
- → CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity(2013)601 cited
- → COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites(2014)419 cited
- → Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection(2014)316 cited
- → Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome(2015)254 cited
- → The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells(2016)249 cited
- → TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity(2014)188 cited
- → Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus(2018)184 cited
- → Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs(2010)183 cited