Randy Hecht
Amgen (United States)(US)
Publications by Year
Research Areas
Fibroblast Growth Factor Research, Kruppel-like factors research, Epigenetics and DNA Methylation, Microfluidic and Capillary Electrophoresis Applications, Regulation of Appetite and Obesity
Most-Cited Works
- → Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice(1995)4,017 cited
- → Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice(2008)1,133 cited
- → Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects(2009)334 cited
- → FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation(2009)177 cited
- → Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes(2012)163 cited
- → Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys(2012)149 cited
- → FGF21 N‐ and C‐termini play different roles in receptor interaction and activation(2008)149 cited
- → Human leptin characterization(1996)117 cited
- → A Novel Fc-FGF21 With Improved Resistance to Proteolysis, Increased Affinity Toward β-Klotho, and Enhanced Efficacy in Mice and Cynomolgus Monkeys(2017)104 cited
- → Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice(2009)104 cited