William J. McClellan

Publications by Year

Research Areas

Asymmetric Synthesis and Catalysis, Cell death mechanisms and regulation, Protease and Inhibitor Mechanisms, Analytical Chemistry and Chromatography, Peptidase Inhibition and Analysis

Most-Cited Works

• → Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL(2007)294 cited
• → A Small-Molecule Inhibitor of Bcl-XL Potentiates the Activity of Cytotoxic Drugs In vitro and In vivo(2006)146 cited
• → Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo(2006)130 cited
• → Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution(2003)66 cited
• → Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors(2017)64 cited
• → Discovery of potent and selective thienopyrimidine inhibitors of Aurora kinases(2011)49 cited
• → Reduction of nanoparticle exposure to welding aerosols by modification of the ventilation system in a workplace(2006)47 cited
• → Conformationally defined adrenergic agents. 1. Design and synthesis of novel .alpha.2-selective adrenergic agents: electrostatic repulsion based conformational prototypes(1985)37 cited
• → A simple, high-yielding method for the methylenation of catechols(1991)33 cited
• → Interaction with the S1β-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors(2004)28 cited