Frank Lovering
Pfizer (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Protein Kinase Regulation and GTPase Signaling, Chemical synthesis and alkaloids, Cell Adhesion Molecules Research
Most-Cited Works
- → Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success(2009)4,214 cited
- → Escape from Flatland 2: complexity and promiscuity(2012)1,365 cited
- → Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay(2017)159 cited
- → Fluorine in Drug Design: A Case Study with Fluoroanisoles(2015)149 cited
- → Discovery of Clinical Candidate 1-{[(2 S ,3 S ,4 S )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design(2017)139 cited
- → Acylguanidines as Small-Molecule β-Secretase Inhibitors(2006)100 cited
- → Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α(2007)79 cited
- → Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization(2005)76 cited
- → Identification of potent and selective MMP-13 inhibitors(2005)70 cited
- → Conformationally restricted inhibitors of the high affinity -glutamate transporter(1993)58 cited