Jennifer J. Bouska
Abbott (United States)(US)Abbott Fund(US)
Publications by Year
Research Areas
Microtubule and mitosis dynamics, PI3K/AKT/mTOR signaling in cancer, PARP inhibition in cancer therapy, DNA Repair Mechanisms, Cancer-related Molecular Pathways
Most-Cited Works
- → ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models(2007)764 cited
- → 5-lipoxygenase inhibitory activity of zileuton.(1990)419 cited
- → Discovering novel ligands for macromolecules using X-ray crystallographic screening(2000)320 cited
- → Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer(2008)266 cited
- → Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo(2005)244 cited
- → Discovery ofN-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitor(2007)184 cited
- → Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors(2005)152 cited
- → Trifluoromethyl ketones as inhibitors of histone deacetylase(2002)147 cited
- → Synthesis and Evaluation of a New Generation of Orally Efficacious Benzimidazole-Based Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors as Anticancer Agents(2009)108 cited
- → Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)(2009)106 cited