J. Howard Jones
Biogen (United States)(US)
Publications by Year
Research Areas
Redox biology and oxidative stress, Genomics, phytochemicals, and oxidative stress, Aldose Reductase and Taurine, Neuroscience and Neuropharmacology Research, Alzheimer's disease research and treatments
Most-Cited Works
- → Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications(2005)224 cited
- → Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators(2019)42 cited
- → ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis(2016)38 cited
- → Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors(2019)34 cited
- → Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo(2021)33 cited
- → Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand(2016)31 cited
- → Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors(2020)23 cited
- → Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo(2021)15 cited
- → Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis(2024)15 cited
- → The quantum theory and the dielectric constant(1924)2 cited