Philip J. Pye
Johnson & Johnson (United States)(US)Janssen (Belgium)(BE)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Cancer Treatment and Pharmacology, Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis, Asymmetric Hydrogenation and Catalysis
Most-Cited Works
- → A New Planar Chiral Bisphosphine Ligand for Asymmetric Catalysis: Highly Enantioselective Hydrogenations under Mild Conditions(1997)370 cited
- → Efficient Synthesis of NK1 Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation(2003)156 cited
- → Kinetic Resolution of rac-4,12-Dibromo[2.2]paracyclophane in a Palladium [2.2]PHANEPHOS Catalyzed Amination(1997)139 cited
- → [2.2]PHANEPHOS-Ruthenium(II) complexes: Highly active asymmetric catalysts for the hydrogenation of β-ketoesters(1998)112 cited
- → An efficient asymmetric hydrogenation approach to the synthesis of the Crixivan® piperazine intermediate(1998)103 cited
- → A Practical Synthesis of a COX-2-Specific Inhibitor(2000)88 cited
- → Development of a Second-Generation, Highly Efficient Manufacturing Route for the HIV Integrase Inhibitor Raltegravir Potassium(2010)50 cited
- → Crystallization-Induced Diastereoselection: Asymmetric Synthesis of Substance P Inhibitors(2002)48 cited
- → Taxane diterpenes 1. Control of relative and absolute stereochemistry in intramolecular pyrylium ylide-alkene cyclizations for the synthesis of taxol precursors(1996)33 cited
- → Efficient and Practical Synthesis of a Potent Anti-MRSA β-Methylcarbapenem Containing a Releasable Side Chain(1999)28 cited