Helen McMiken
AstraZeneca (United Kingdom)(GB)
Publications by Year
Research Areas
Tuberculosis Research and Epidemiology, Biochemical and Molecular Research, Microtubule and mitosis dynamics, Cancer therapeutics and mechanisms, Cancer-related Molecular Pathways
Most-Cited Works
- → SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors(2005)125 cited
- → Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis(2013)100 cited
- → Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor(2004)98 cited
- → Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis(2013)46 cited
- → Structure Guided Lead Generation for M. tuberculosis Thymidylate Kinase (Mtb TMK): Discovery of 3-Cyanopyridone and 1,6-Naphthyridin-2-one as Potent Inhibitors(2014)44 cited
- → Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors(2008)30 cited
- → Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor(2009)
- → Aurora A kinase activated mutant (T287D) in complex with a 5- aminopyrimidinyl quinazoline inhibitor(2005)