Louise Boulet

Publications by Year

Research Areas

Phosphodiesterase function and regulation, Asthma and respiratory diseases, Cholinesterase and Neurodegenerative Diseases, Mitochondrial Function and Pathology, RNA and protein synthesis mechanisms

Most-Cited Works

• Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF).(1992)
• → Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors(2007)128 cited
• → Deletion of Microsomal Prostaglandin E2 (PGE2) Synthase-1 Reduces Inducible and Basal PGE2 Production and Alters the Gastric Prostanoid Profile(2004)119 cited
• → Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey(2001)79 cited
• → Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity(2003)66 cited
• → Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors(2009)61 cited
• → Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor(2005)30 cited
• → Mistranslation in twelve Escherichia coli ribosomal proteins. Cysteine misincorporation at neutral amino acid residues other than tryptophan(1987)29 cited
• → Comparison of inhibition of ovalbumin-induced bronchoconstriction in guinea pigs and in vitro inhibition of tumor necrosis factor-α formation with phosphodiesterase 4 (PDE4) selective inhibitors(2002)27 cited
• → [40] Use of myoblast cultures to study mitochondrial myopathies(1996)25 cited