Robert Koenig
Center for Global Development(US)Novartis (United States)(US)
Publications by Year
Research Areas
Protein Tyrosine Phosphatases, Galectins and Cancer Biology, Bioactive Compounds and Antitumor Agents, Atherosclerosis and Cardiovascular Diseases, Synthesis and biological activity
Most-Cited Works
- → Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer(2020)210 cited
- → Dual Allosteric Inhibition of SHP2 Phosphatase(2018)127 cited
- → 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors(2019)86 cited
- → Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors(2019)80 cited
- → S227928: A Novel Anti-CD74 ADC with MCL-1 Inhibitor Payload for the Treatment of Acute Myeloid Leukemia (AML) and Other Hematologic Malignancies(2024)5 cited
- → Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors(2019)2 cited
- → Correction to 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors(2019)2 cited
- → Abstract 2808: Simultaneous inhibition of SHP2 phosphatase at two allosteric sites(2018)1 cited
- Perturbations to the Allosteric Regulation of Carbamoyl Phosphate Synthetase upon Removal of Interfacial Restraints(2017)
- → The Isolated Large Subunit of E. coli Carbamoylphosphate Synthetase Deviates from Kinetic Mechanism and Allosteric Behavior of the Holoenzyme(2015)