Snahel Patel
Frontier Medicines (United States)
Publications by Year
Research Areas
Cell death mechanisms and regulation, Genomics, phytochemicals, and oxidative stress, 3D Printing in Biomedical Research, interferon and immune responses, Pluripotent Stem Cells Research
Most-Cited Works
- → Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease(2017)160 cited
- → RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases(2019)141 cited
- → Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models(2014)86 cited
- → Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer’s Disease(2017)71 cited
- → Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes(2021)61 cited
- → Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N -(1 H -Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)(2015)58 cited
- → From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors(2017)57 cited
- → Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: Alleviating hERG interactions through structure based design(2009)56 cited
- → Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy(2022)45 cited
- → RIP1 kinase activity is critical for skin inflammation but not for viral propagation(2020)39 cited