Michael J. Eck
Harvard University(US)Dana-Farber Cancer Institute(US)
Publications by Year
Research Areas
Lung Cancer Treatments and Mutations, HER2/EGFR in Cancer Research, Cancer therapeutics and mechanisms, Protein Kinase Regulation and GTPase Signaling, Monoclonal and Polyclonal Antibodies Research
Most-Cited Works
- → EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy(2004)9,380 cited
- → EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib(2005)3,917 cited
- → Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis(2005)2,972 cited
- → The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP(2008)2,085 cited
- → Three-dimensional structure of the tyrosine kinase c-Src(1997)1,414 cited
- → Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity(2007)1,146 cited