Lieve Umans
VIB-KU Leuven Center for Cancer Biology(BE)
Publications by Year
Research Areas
Congenital heart defects research, TGF-β signaling in diseases, Angiogenesis and VEGF in Cancer, Lymphatic System and Diseases, Cardiac Fibrosis and Remodeling
Most-Cited Works
- → Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency(1999)521 cited
- → Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin(1998)301 cited
- → Neuronal Deficiency of Presenilin 1 Inhibits Amyloid Plaque Formation and Corrects Hippocampal Long-Term Potentiation But Not a Cognitive Defect of Amyloid Precursor Protein [V717I] Transgenic Mice(2002)238 cited
- → Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades(2012)221 cited
- → Conditional Deletion of Smad1 and Smad5 in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in Mice(2007)210 cited
- → TDP2–Dependent Non-Homologous End-Joining Protects against Topoisomerase II–Induced DNA Breaks and Genome Instability in Cells and In Vivo(2013)162 cited
- → Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.(1993)149 cited
- → Functional Redundancy of TGF-beta Family Type I Receptors and Receptor-Smads in Mediating Anti-Müllerian Hormone-Induced Müllerian Duct Regression in the Mouse1(2008)111 cited
- → TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1(2012)106 cited
- → The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization(2011)103 cited