Jason R. Thomas
Novartis (Switzerland)(CH)Novartis (China)(CN)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, RNA and protein synthesis mechanisms, RNA Research and Splicing, Multiple Myeloma Research and Treatments, Ubiquitin and proteasome pathways
Most-Cited Works
- → Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo(2014)724 cited
- → Targeting RNA with Small Molecules(2008)642 cited
- → SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice(2015)426 cited
- → Harnessing the anti-cancer natural product nimbolide for targeted protein degradation(2019)412 cited
- → Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications(2019)325 cited
- → Drug discovery considerations in the development of covalent inhibitors(2013)195 cited
- → Size-Specific Ligands for RNA Hairpin Loops(2005)150 cited
- → Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes(2013)130 cited
- → Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti‐Cancer Properties(2015)107 cited
- → CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma(2019)87 cited