Joseph J. Nunes
Publications by Year
Research Areas
Synthesis and biological activity, Quinazolinone synthesis and applications, Protein Kinase Regulation and GTPase Signaling, Sirtuins and Resveratrol in Medicine, Biochemical effects in animals
Most-Cited Works
- → Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes(2007)1,679 cited
- → Dramatic rate accelerations of Diels-Alder reactions in 5 M lithium perchlorate-diethyl ether: the cantharidin problem reexamined(1990)324 cited
- → Discovery of Imidazo[1,2- b ]thiazole Derivatives as Novel SIRT1 Activators(2009)117 cited
- → Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators(2008)90 cited
- → Stereocontrolled total synthesis of (.+-.)-quinocarcin(1988)71 cited
- → Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity(2006)67 cited
- → Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity(2008)63 cited
- → Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity(2006)61 cited
- → Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR(2007)48 cited
- → Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties(2007)41 cited