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Tip W. Loo | doi.page

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Tip W. Loo

University of Toronto(CA)

Publications by Year

Research Areas

Drug Transport and Resistance Mechanisms, HIV/AIDS drug development and treatment, Pharmacological Effects and Toxicity Studies, Cystic Fibrosis Research Advances, Adenosine and Purinergic Signaling

Most-Cited Works

→ Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase(1989)570 cited
→ Membrane Topology of a Cysteine-less Mutant of Human P-glycoprotein(1995)255 cited
→ Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators(1997)224 cited
→ Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein.(1993)218 cited
→ Recent Progress in Understanding the Mechanism of P-Glycoprotein-mediated Drug Efflux(2005)209 cited
→ Location of the Rhodamine-binding Site in the Human Multidrug Resistance P-glycoprotein(2002)201 cited
→

Defining the Drug-binding Site in the Human Multidrug Resistance P-glycoprotein Using a Methanethiosulfonate Analog of Verapamil, MTS-verapamil

(2001)

189 cited

→ Simultaneous Binding of Two Different Drugs in the Binding Pocket of the Human Multidrug Resistance P-glycoprotein(2003)178 cited

→ Rapid Purification of Human P-glycoprotein Mutants Expressed Transiently in HEK 293 Cells by Nickel-Chelate Chromatography and Characterization of their Drug-stimulated ATPase Activities(1995)178 cited

→ Reconstitution of drug-stimulated ATPase activity following co-expression of each half of human P-glycoprotein as separate polypeptides.(1994)176 cited