Frédéric Donche
GlaxoSmithKline (France)(FR)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, RNA Interference and Gene Delivery, Metabolism, Diabetes, and Cancer, NF-κB Signaling Pathways
Most-Cited Works
- → Identification of a novel series of BET family bromodomain inhibitors: Binding mode and profile of I-BET151 (GSK1210151A)(2012)207 cited
- → From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151(2012)118 cited
- → Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPARα Agonists. 1. Discovery of a Novel Series of Potent HDLc Raising Agents(2007)117 cited
- → Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase(2019)68 cited
- → Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity(2008)16 cited
- → Discovery of Pyridones As Oral AMPK Direct Activators(2013)14 cited
- → N-Terminal Bromodomain of Human BRD2 With tbutyl-phenyl-amino- dimethyl-oxazolyl-quinoline-carboxylic acid(2012)