Alfred Zimmerlin
Novartis (Switzerland)(CH)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Analytical Chemistry and Chromatography, Synthesis and biological activity, Pesticide and Herbicide Environmental Studies, Melanoma and MAPK Pathways
Most-Cited Works
- → Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase(2011)487 cited
- → The Origin of the Oxidative Burst in Plants(1995)381 cited
- → Plant cytochrome p450(1994)258 cited
- → Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase(2020)151 cited
- → Metabolic Soft Spot Identification and Compound Optimization in Early Discovery Phases Using MetaSite and LC-MS/MS Validation(2008)116 cited
- → Molecular identification and expression of the peroxidase responsible for the oxidative burst in French bean (Phaseolus vulgaris L.) and related members of the gene family(2001)94 cited
- → Tissue and subcellular immunolocalisation of enzymes of lignin synthesis in differentiating and wounded hypocotyl tissue of French bean (Phaseolus vulgaris L.)(1994)93 cited
- → CYP3A Time-Dependent Inhibition Risk Assessment Validated with 400 Reference Drugs(2011)90 cited
- → Aryl Hydroxylation of the Herbicide Diclofop by a Wheat Cytochrome P-450 Monooxygenase(1992)88 cited