Lewis Whitehead
Intarcia Therapeutics (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Histone Deacetylase Inhibitors Research, Protein Degradation and Inhibitors, Pharmacogenetics and Drug Metabolism, Protein Structure and Dynamics
Most-Cited Works
- → Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors(2011)153 cited
- → Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection(2012)116 cited
- → Small Molecule-facilitated Degradation of ANO1 Protein(2014)83 cited
- → Optimization of the in Vitro Cardiac Safety of Hydroxamate-Based Histone Deacetylase Inhibitors(2011)64 cited
- → An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential(2011)60 cited
- → Molecular dynamics simulation of the hydrocarbon region of a biomembrane using a reduced representation model(2001)56 cited
- → Identification of Elongation Factor G as the Conserved Cellular Target of Argyrin B(2012)51 cited
- → Automated Ligand- and Structure-Based Protocol for in Silico Prediction of Human Serum Albumin Binding(2013)50 cited
- → Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway(2012)47 cited
- → Antibacterial Optimization of 4-Aminothiazolyl Analogues of the Natural Product GE2270 A: Identification of the Cycloalkylcarboxylic Acids(2011)41 cited