Aihe Zhou
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Cytokine Signaling Pathways and Interactions, Pharmacogenetics and Drug Metabolism, Pancreatic function and diabetes, Metabolism, Diabetes, and Cancer
Most-Cited Works
- → Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition(2016)258 cited
- → Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development(2016)157 cited
- → A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors(2013)125 cited
- → Discovery of Potent and Selective Pyrazolopyrimidine Janus Kinase 2 Inhibitors(2012)89 cited
- → Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists(2015)70 cited
- → A Pentacyclic Aurora Kinase Inhibitor (AKI-001) with High in Vivo Potency and Oral Bioavailability(2008)58 cited
- → Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice(2016)56 cited
- → Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase(2014)44 cited
- → Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase(2014)22 cited
- → Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase(2014)21 cited