Rachel Lakey
Wellcome Centre for Mitochondrial Research(GB)Newcastle University(GB)
Publications by Year
Research Areas
Acute Ischemic Stroke Management, Osteoarthritis Treatment and Mechanisms, Protease and Inhibitor Mechanisms, Cell Adhesion Molecules Research, Venous Thromboembolism Diagnosis and Management
Most-Cited Works
- → Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption(2005)188 cited
- → Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: Implications for cartilage degradation in arthritis(2006)121 cited
- → Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up(2012)89 cited
- → Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent(2008)63 cited
- → Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation(2010)42 cited
- → Effect of an Enhanced Paramedic Acute Stroke Treatment Assessment on Thrombolysis Delivery During Emergency Stroke Care(2020)33 cited
- → Gingival fibroblasts grown from cyclosporin‐treated patients show a reduced production of matrix metalloproteinase‐1 (MMP‐1) compared with normal gingival fibroblasts, and cyclosporin down‐regulates the production of MMP‐1 stimulated by pro‐inflammatory cytokines(2007)23 cited
- → A novel paradigm for dendritic cells as effectors of cartilage destruction(2008)21 cited
- → Sulfasalazine blocks the release of proteoglycan and collagen from cytokine stimulated cartilage and down-regulates metalloproteinases(2009)20 cited
- → Paramedic Acute Stroke Treatment Assessment (PASTA): study protocol for a randomised controlled trial(2019)15 cited