Sonnet S. Davis
Denali Therapeutics (United States)(US)
Publications by Year
Research Areas
Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments, Lysosomal Storage Disorders Research, Endoplasmic Reticulum Stress and Disease, RNA regulation and disease
Most-Cited Works
- → Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype(2015)1,162 cited
- → TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge(2020)713 cited
- → Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia(2020)240 cited
- → Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease(2022)237 cited
- → Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic(2021)215 cited
- → A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models(2023)214 cited
- → Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice(2020)197 cited
- → Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila(2015)175 cited
- → Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis(2021)152 cited
- → Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist(2023)124 cited