David Hargreaves
AstraZeneca (Australia)(AU)AstraZeneca (Brazil)(BR)AstraZeneca (Poland)(PL)AstraZeneca (Germany)(DE)
Publications by Year
Research Areas
Enzyme Structure and Function, Monoclonal and Polyclonal Antibodies Research, Cell death mechanisms and regulation, Lung Cancer Treatments and Mutations, HER2/EGFR in Cancer Research
Most-Cited Works
- → Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia(2018)480 cited
- → Crystal Structure of DNA Recombination Protein RuvA and a Model for Its Binding to the Holliday Junction(1996)167 cited
- → Crystal structure of E.coli RuvA with bound DNA Holliday junction at 6 Å resolution(1998)136 cited
- → Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6(2018)136 cited
- → Crystal Structures of Human ADAMTS-1 Reveal a Conserved Catalytic Domain and a Disintegrin-like Domain with a Fold Homologous to Cysteine-Rich Domains(2007)95 cited
- → Structure of IL-17A in Complex with a Potent, Fully Human Neutralizing Antibody(2009)81 cited