Xinshan Kang
Publications by Year
Research Areas
Quinazolinone synthesis and applications, Protein Kinase Regulation and GTPase Signaling, Chronic Myeloid Leukemia Treatments, Protein Structure and Dynamics, DNA and Nucleic Acid Chemistry
Most-Cited Works
- → Hierarchical Database Screenings for HIV-1 Reverse Transcriptase Using a Pharmacophore Model, Rigid Docking, Solvation Docking, and MM−PB/SA(2005)63 cited
- → Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitors(2012)61 cited
- → Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction(2007)55 cited
- → Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays(2006)47 cited
- → Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration(2008)44 cited
- → Inhibitors of ABL and the ABL-T315I Mutation(2008)41 cited
- → Calculation of ligand‐nucleic acid binding free energies with the generalized‐born model in DOCK(2003)35 cited
- → Role of Heme in Structural Organization of CytochromecProbed by Semisynthesis(1999)30 cited
- → Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors(2006)28 cited
- → The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes(2007)24 cited