George A. Moniz
Biogen (United States)(US)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Chemical Synthesis and Analysis, Cyclopropane Reaction Mechanisms, Synthetic Organic Chemistry Methods, Hormonal Regulation and Hypertension
Most-Cited Works
- → E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling(2015)84 cited
- → Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)(2010)80 cited
- → Development of a Rhodium Carbenoid-Initiated Claisen Rearrangement for the Enantioselective Synthesis of α-Hydroxy Carbonyl Compounds(1999)74 cited
- → An Aldol-Based Synthesis of (+)-Peloruside A, A Potent Microtubule Stabilizing Agent(2009)67 cited
- → Catalyst-Based Control of [2,3]- and [3,3]-Rearrangement in α-Diazoketone-Derived Propargyloxy Enols(2001)62 cited
- → A highly enantioselective catalyst for asymmetric hydroformylation of [2.2.1]-bicyclic olefins(2005)56 cited
- → A Baeyer-Villiger Oxidation Specifically Catalyzed by Human Flavin-Containing Monooxygenase 5(2010)50 cited
- → 2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors: Enzyme−Ligand Co-Crystal Structure and Demonstration of Pharmacodynamic Effects in C57Bl/6 Mice(2008)49 cited
- → Rhodium Carbenoid-Initiated Claisen Rearrangement: Scope and Mechanistic Observations(1999)48 cited
- → Efficient Syntheses of (α-Fluoropropargyl)phosphonate Esters(1996)45 cited