Jaclyn N. Highland
University of Maryland, Baltimore(US)VA Maryland Health Care System(US)
Publications by Year
Research Areas
Tryptophan and brain disorders, Treatment of Major Depression, Neuroscience and Neuropharmacology Research, Stress Responses and Cortisol, Neurotransmitter Receptor Influence on Behavior
Most-Cited Works
- → Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms(2018)1,217 cited
- → ( 2R,6R )-hydroxynorketamine exerts mGlu 2 receptor-dependent antidepressant actions(2019)152 cited
- → Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor(2022)131 cited
- → A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice(2017)107 cited
- → Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications(2021)93 cited
- → (R)‐Ketamine exerts antidepressant actions partly via conversion to (2R,6R)‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses(2019)82 cited
- → Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of (2R,6R)-hydroxynorketamine(2018)59 cited
- → Group II metabotropic glutamate receptor blockade promotes stress resilience in mice(2019)55 cited
- → Sex-dependent metabolism of ketamine and (2R,6R)-hydroxynorketamine in mice and humans(2021)30 cited
- → Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (2,6)- and (5R)-Methyl-(2R,6R)-hydroxynorketamines(2022)25 cited