Rajeev S. Bhide

Publications by Year

Research Areas

Angiogenesis and VEGF in Cancer, PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, Cancer, Hypoxia, and Metabolism, HER2/EGFR in Cancer Research

Most-Cited Works

• → Discovery of Brivanib Alaninate ((S)-((R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)(2008)141 cited
• → Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity(2000)134 cited
• → Discovery and Preclinical Studies of (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In Vivo Active Potent VEGFR-2 Inhibitor(2006)132 cited
• → Discovery of the Pyrrolo[2,1-f][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template(2004)92 cited
• → Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular andin VivoActivity(1996)88 cited
• → The Antiangiogenic Activity in Xenograft Models of Brivanib, a Dual Inhibitor of Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinases(2010)71 cited
• → Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors(2005)63 cited
• → Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors(2006)51 cited
• → Concise and Efficient Synthesis of 4-Fluoro-1H-pyrrolo[2,3-b]pyridine(2003)47 cited
• → Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase(1999)41 cited