Bethany L. Kormos
Pfizer (United States)(US)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, RNA and protein synthesis mechanisms, Protein Structure and Dynamics, Phosphodiesterase function and regulation, Crystallization and Solubility Studies
Most-Cited Works
- → Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor(2012)420 cited
- → Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor(2014)180 cited
- → Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs(2017)175 cited
- → Do Collective Atomic Fluctuations Account for Cooperative Effects? Molecular Dynamics Studies of the U1A−RNA Complex(2006)55 cited
- → Dopamine D3 receptor antagonist reveals a cryptic pocket in aminergic GPCRs(2018)53 cited
- → A study of collective atomic fluctuations and cooperativity in the U1A–RNA complex based on molecular dynamics simulations(2006)45 cited
- → Improving the Odds of Success in Drug Discovery: Choosing the Best Compounds for in Vivo Toxicology Studies(2013)43 cited
- → Affinity and Specificity of Protein U1A-RNA Complex Formation Based on an Additive Component Free Energy Model(2007)41 cited
- → Electronic Structure and Bonding in Hexacoordinate Silyl–Palladium Complexes Support from the National Science Foundation (CHE-9876792) is gratefully acknowledged.(2002)40 cited
- → Late-Stage Microsomal Oxidation Reduces Drug–Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189(2018)38 cited