Jaap Twisk
UniQure (Netherlands)(NL)
Publications by Year
Research Areas
Cholesterol and Lipid Metabolism, Virus-based gene therapy research, Diabetes and associated disorders, Drug Transport and Resistance Mechanisms, Lipid metabolism and disorders
Most-Cited Works
- → Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial(2012)398 cited
- → Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues(2002)346 cited
- → The role of the LDL receptor in apolipoprotein B secretion(2000)245 cited
- → Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver(2003)236 cited
- → Intramuscular Administration of AAV1-Lipoprotein Lipase S447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients(2008)207 cited
- → Effect of Alipogene Tiparvovec (AAV1-LPLS447X) on Postprandial Chylomicron Metabolism in Lipoprotein Lipase-Deficient Patients(2012)163 cited
- → Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria(2016)140 cited
- → Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection(2008)139 cited
- → Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice(2004)131 cited
- → Immune Responses to Intramuscular Administration of Alipogene Tiparvovec (AAV1-LPL S447X ) in a Phase II Clinical Trial of Lipoprotein Lipase Deficiency Gene Therapy(2013)129 cited