Miriam Burman
GlaxoSmithKline (United States)(US)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Asthma and respiratory diseases, Ion channel regulation and function
Most-Cited Works
- → 1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma(1998)150 cited
- → Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B(1999)144 cited
- → Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.(1992)139 cited
- → A low-Km, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain. Cloning and expression of cDNA, biochemical characterization of recombinant protein, and tissue distribution of mRNA.(1993)130 cited
- → Mapping the functional domains of human recombinant phosphodiesterase 4A: structural requirements for catalytic activity and rolipram binding.(1996)117 cited
- → Association of the anti-inflammatory activity of phosphodiesterase 4 (PDE4) inhibitors with either inhibition of PDE4 catalytic activity or competition for [3H]rolipram binding(1996)106 cited
- → Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site.(1995)105 cited
- → Pharmacological Characterization of GSK573719 (Umeclidinium): A Novel, Long-Acting, Inhaled Antagonist of the Muscarinic Cholinergic Receptors for Treatment of Pulmonary Diseases(2013)77 cited
- Inhibition of the low km cyclic AMP phosphodiesterase in intact canine trachealis by SK&F 94836: mechanical and biochemical responses.(1988)
- → Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis.(1991)55 cited