Hilda Solanoy
Denali Therapeutics (United States)(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Endoplasmic Reticulum Stress and Disease, RNA regulation and disease, Neuroinflammation and Neurodegeneration Mechanisms, Amyotrophic Lateral Sclerosis Research
Most-Cited Works
- → TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge(2020)713 cited
- → Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations(2012)373 cited
- → Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys(2020)340 cited
- → Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier(2013)261 cited
- → Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease(2022)237 cited
- → Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic(2021)215 cited
- → A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models(2023)214 cited
- → Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice(2020)197 cited
- → Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease(2017)160 cited
- → Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia(2022)114 cited