Lois Commodore
Idera Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Chronic Myeloid Leukemia Treatments, Eosinophilic Disorders and Syndromes, Chronic Lymphocytic Leukemia Research, Cancer, Hypoxia, and Metabolism, Lanthanide and Transition Metal Complexes
Most-Cited Works
- → AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance(2009)1,234 cited
- → Discovery of 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant(2010)358 cited
- → Structural Mechanism of the Pan‐BCR‐ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance(2010)282 cited
- → Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors(2013)84 cited
- → Interfacial Basic Cluster in Annexin V Couples Phospholipid Binding and Trimer Formation on Membrane Surfaces(2003)39 cited
- → Structural Analysis of DFG‐in and DFG‐out Dual Src‐Abl Inhibitors Sharing a Common Vinyl Purine Template(2009)28 cited
- → Discovery of 5-(arenethynyl) hetero-monocyclic derivatives as potent inhibitors of BCR–ABL including the T315I gatekeeper mutant(2011)18 cited
- → Abstract 2671: Structural analysis of the inhibitory mechanism of AP24534, a pan-BCR-ABL inhibitor overriding the T315I gatekeeper mutation(2010)
- → Crystal structure of rabbit LDHA in complex with AP27460(2012)
- → Abstract 3236: Small molecule inhibitors of choline kinase lead to reduced phosphocholine levels and induction of apoptosis in cancer cells(2012)