Christian Harcken
Boehringer Ingelheim (United States)(US)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, Asymmetric Hydrogenation and Catalysis, Synthetic Organic Chemistry Methods, Chemical Synthesis and Analysis, Estrogen and related hormone effects
Most-Cited Works
- → RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients(2018)309 cited
- → A GPBAR1 (TGR5) Small Molecule Agonist Shows Specific Inhibitory Effects on Myeloid Cell Activation In Vitro and Reduces Experimental Autoimmune Encephalitis (EAE) In Vivo(2014)84 cited
- → Improved E-Selectivity in the Wittig Reaction of Stabilized Ylides with α-Alkoxyaldehydes and Sugar Lactols(2001)65 cited
- → Synthesis of Optically Active Butenolides and γ‐Lactones by the Sharpless Asymmetric Dihydroxylation of β,γ‐Unsaturated Carboxylic Esters(1997)63 cited
- → An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients(2018)47 cited
- → BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis(2018)46 cited
- → Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics(2010)45 cited
- → G Protein–Coupled Bile Acid Receptor 1 Stimulation Mediates Arterial Vasodilation through a KCa1.1 (BKCa)–Dependent Mechanism(2014)43 cited
- → Total Syntheses of (−)-Grandinolide and (−)-Sapranthin by the Sharpless Asymmetric Dihydroxylation of Methyltrans-3-Pentenoate: Elucidation of the Stereostructure of (−)-Sapranthin(1998)43 cited
- → Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton’s Tyrosine Kinase(2016)39 cited