Shyam K. Sharan
National Institutes of Health(US)National Cancer Institute(US)Cancer Genetics (United States)(US)Center for Cancer Research(US)
Publications by Year
Research Areas
DNA Repair Mechanisms, CRISPR and Genetic Engineering, BRCA gene mutations in cancer, PARP inhibition in cancer therapy, Animal Genetics and Reproduction
Most-Cited Works
- → Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2(1997)1,067 cited
- → Replication fork stability confers chemoresistance in BRCA-deficient cells(2016)911 cited
- → Recombineering: a homologous recombination-based method of genetic engineering(2009)811 cited
- → Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions(2002)248 cited
- → Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models(2005)223 cited
- → Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155(2011)221 cited