Jean Dinh
Simcyp (United Kingdom)(GB)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Pharmaceutical studies and practices, Drug Transport and Resistance Mechanisms, Antibiotics Pharmacokinetics and Efficacy, Diet and metabolism studies
Most-Cited Works
- → Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy(2019)193 cited
- → Ten Years’ Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics(2018)163 cited
- → Potential Contribution of Cytochrome P450 2B6 to Hepatic 4-Hydroxycyclophosphamide Formation In Vitro and In Vivo(2011)55 cited
- → Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research(2015)29 cited
- → Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children(2016)27 cited
- → Is this the end for ranitidine? NDMA presence continues to confound(2021)24 cited
- → Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver(2021)22 cited
- → Physiologically Based Pharmacokinetics Modeling in the Neonatal Population—Current Advances, Challenges, and Opportunities(2023)15 cited
- → Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity(2023)14 cited
- → Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model(2024)12 cited