Thierry Lavé
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Lung Cancer Treatments and Mutations, Analytical Chemistry and Chromatography, Computational Drug Discovery Methods
Most-Cited Works
- → PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance(2011)198 cited
- → PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach(2011)170 cited
- → Prediction of intestinal absorption: comparative assessment of gastroplus™ and idea™(2002)168 cited
- → Influence of molecular size on tissue distribution of antibody fragments(2015)158 cited
- → PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution(2011)133 cited
- → Applications of Physiologically Based Absorption Models in Drug Discovery and Development(2008)121 cited
- → Challenges and opportunities with modelling and simulation in drug discovery and drug development(2007)115 cited
- → Development of a Physiologically Based Model for Oseltamivir and Simulation of Pharmacokinetics in Neonates and Infants(2011)113 cited
- → An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery(2005)108 cited
- → Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling(2017)107 cited