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Zeger Debyser | doi.page

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Zeger Debyser

Hermitage Museum(US)KU Leuven(BE)

Publications by Year

Research Areas

HIV Research and Treatment, HIV/AIDS drug development and treatment, Virus-based gene therapy research, Biochemical and Molecular Research, RNA Interference and Gene Delivery

Most-Cited Works

→ HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells(2002)695 cited
→ LEDGF/p75 Is Essential for Nuclear and Chromosomal Targeting of HIV-1 Integrase in Human Cells(2003)484 cited
→ Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication(2010)464 cited
→ Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale(2010)329 cited
→ Comparative Analysis of Adeno-Associated Viral Vector Serotypes 1, 2, 5, 7, And 8 in Mouse Brain(2007)298 cited
→ Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100(1994)295 cited
→

Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event.

(1992)

245 cited

→ Transportin-SR2 Imports HIV into the Nucleus(2008)240 cited

→ Integrase Mutants Defective for Interaction with LEDGF/p75 Are Impairedin Chromosome Tethering and HIV-1Replication(2005)233 cited

→ Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus(2006)209 cited