Igor Mochalkin
Publications by Year
Research Areas
Click Chemistry and Applications, Biotin and Related Studies, Melanoma and MAPK Pathways, Computational Drug Discovery Methods, Protein Structure and Dynamics
Most-Cited Works
- → Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers(2015)305 cited
- → Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects(2020)296 cited
- → A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides(2000)202 cited
- → Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120(2016)168 cited
- → A class of selective antibacterials derived from a protein kinase inhibitor pharmacophore(2009)159 cited
- → Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases(2019)137 cited
- → Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches(2009)105 cited
- → Structure and Ligand Binding Determinants of the Recombinant Kringle 5 Domain of Human Plasminogen,(1998)87 cited
- → Structural evidence for substrate‐induced synergism and half‐sites reactivity in biotin carboxylase(2008)85 cited
- → Crystal structure of native chicken fibrinogen at 5.5-Å resolution(2000)75 cited