Kirupa Sathasivam
Queen Mary University of London(GB)Huntington's Disease Association(GB)MRC Prion Unit(GB)University College London(GB)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Muscle Physiology and Disorders, Neurological disorders and treatments, Ubiquitin and proteasome pathways
Most-Cited Works
- → Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice(1996)3,074 cited
- → Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease(2003)838 cited
- → Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease(2013)528 cited
- → Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease(2010)336 cited
- → Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage(2007)321 cited
- → Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation