Kristine S. Klos
Minnesota Department of Health(US)
Publications by Year
Research Areas
HER2/EGFR in Cancer Research, Cancer Cells and Metastasis, Angiogenesis and VEGF in Cancer, PI3K/AKT/mTOR signaling in cancer, Cell Adhesion Molecules Research
Most-Cited Works
- → PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients(2004)1,856 cited
- → Activation of the Akt/Mammalian Target of Rapamycin/4E-BP1 Pathway by ErbB2 Overexpression Predicts Tumor Progression in Breast Cancers(2004)312 cited
- → ErbB2 Increases Vascular Endothelial Growth Factor Protein Synthesis via Activation of Mammalian Target of Rapamycin/p70S6K Leading to Increased Angiogenesis and Spontaneous Metastasis of Human Breast Cancer Cells(2006)200 cited
- → Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-β1 in human breast cancer cells(2001)169 cited
- → The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage(2009)129 cited
- → ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinoma(2002)120 cited
- → Combined trastuzumab and paclitaxel treatment better inhibits ErbB‐2‐mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone(2003)110 cited
- Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells.(2002)
- → ErbB2 Promotes Src Synthesis and Stability: Novel Mechanisms of Src Activation That Confer Breast Cancer Metastasis(2005)106 cited
- → Separating Stem Cells by Flow Cytometry: Reducing Variability for Solid Tissues(2009)72 cited