David H. Perlmutter
Washington University in St. Louis(US)
Publications by Year
Research Areas
Endoplasmic Reticulum Stress and Disease, Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Autophagy in Disease and Therapy, Genetics, Aging, and Longevity in Model Organisms
Most-Cited Works
- → Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.(1986)583 cited
- → Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity(1996)368 cited
- → A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency.(1994)291 cited
- → Retention of mutant α1-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response(2000)271 cited
- → C. elegans in high-throughput drug discovery(2013)265 cited
- → Chemical Chaperones: A Pharmacological Strategy for Disorders of Protein Folding and Trafficking(2002)253 cited