Huai‐Xiang Hao
Novartis (Switzerland)(CH)
Publications by Year
Research Areas
Protein Tyrosine Phosphatases, Melanoma and MAPK Pathways, Synthesis and biological activity, PI3K/AKT/mTOR signaling in cancer, Pancreatic function and diabetes
Most-Cited Works
- → SDH5 , a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma(2009)701 cited
- → Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling(2020)159 cited
- → Dual Allosteric Inhibition of SHP2 Phosphatase(2018)127 cited
- → SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors(2019)91 cited
- → PAS kinase is required for normal cellular energy balance(2007)72 cited
- → Infigratinib Mediates Vascular Normalization, Impairs Metastasis, and Improves Chemotherapy in Hepatocellular Carcinoma(2018)59 cited
- → Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers(2019)53 cited
- → Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR(2020)40 cited
- → The role of PAS kinase in regulating energy metabolism(2008)39 cited
- → Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization(2010)34 cited