Iwan J. P. de Esch
Vrije Universiteit Amsterdam(NL)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Mast cells and histamine, Computational Drug Discovery Methods, Chemical Synthesis and Analysis, Chemokine receptors and signaling
Most-Cited Works
- → The histamine H3 receptor: from gene cloning to H3 receptor drugs(2005)481 cited
- → Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen(2019)354 cited
- → KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space(2013)301 cited
- → Ligand efficiency as a guide in fragment hit selection and optimization(2010)244 cited
- → The histamine H receptor as a new therapeutic target for inflammation(2005)225 cited
- → Keynote review: Histamine H3 receptor antagonists reach out for the clinic(2005)211 cited
- → Crystal Structure-Based Virtual Screening for Fragment-like Ligands of the Human Histamine H Receptor